Role of microRNAs as novel diagnostic biomarkers and potential therapeutic targets for hearing disorders (Review)

The ear is a complex structure consisting of the outer, middle and inner ear. For proper function auditory system, development all these parts needs to be highly organized. Any alterations in this chain events can lead hearing loss or other impairments, such as dizziness, tinnitus balance. Of note, several external internal elements, including noise exposure, ototoxic drugs, aging, well environmental genetic factors, have been widely associated with loss. Over years, growing body evidence has indicated that microRNAs (miRNAs/miRs) play critical role function, suggesting an altered pattern miRNA expression may involved progression pathological conditions. On bases, present review article aimed summarize miRNAs disorders. Although further studies are warranted provide more in‑depth knowledge implicated mechanisms action, according current data, used novel diagnostic biomarkers for early detection In addition, related signaling pathways represent potential therapeutic targets treatment loss, inflammation vestibular schwannoma.